Poison first appeared in the side-scrolling action game known as Final Fight. The character was originally planned to be female, but was changed to a male transvestite due to the suggestion that hitting women were considered rude in America during the game’s release. When asked about the matter, Street Fighter IV’s producer Ono Yoshinori stated:
“Let's set the record straight: In North America, Poison is officially a post-op transsexual. But in Japan, she simply tucks her business away to look female.”
Interesting information on this character that I’ve never even heard of. Hope that doesn’t scare her fans away… Thanks to Michelle for sharing this!